Karyotyping

You will work in groups of two on this activity.

1. Go to the following website: http://learn.genetics.utah.edu/units/disorders/karyotype/
2. Answer the following questions: What is a chromosome? What is a genetic disorder?
3. Go to the following website: http://www.ygyh.org/
4. Click on each example of genetic disorders and describe the characteristics and the chromosomal abnormalities.
5. Go back to the following website: http://learn.genetics.utah.edu/units/disorders/karyotype/
6. Click on “What Are Chromosomes”
7. Answer the following questions: Why do chromosomes have a band stripped appearance? Why do scientists look at chromosomes?
8. Return to the previous page by clicking on "Heredity and Traits"
   
9. Click on “How Do Scientist Read Chromosomes”
10. Answer the following questions: What three key features are used to identify chromosomes similarities and differences? What are centromeres for?
11. Return to the previous page by clicking on "Heredity and Traits"
    
12. Click on “Making a Karyotype”
13. Answer the following questions: What is a karyotype? How are karyotypes arranged?
14. Complete the activity Matching up chromosomes in a Karyotype.
    
15. Print out completed karyotype and submit for a grade.
16. Return to the previous page by clicking on "Heredity and Traits"
17. Now click on “Using Karyotypes to Predict Genetic Disorders”
18. Read and watch all animations 
19. Answer the questions below:
20. A normal human karyotype has 46 chromosomes: ________pairs of autosomes and ______ sex chromosomes
21. If eggs and sperm only have one set of chromosomes, then how do we end up with 46 chromosomes?
22. What happens when a person has:
    
    • Too many or too few chromosomes? (Give examples)
    • Missing pieces of chromosomes? (Give examples)
    • Mixed up pieces of chromosomes? (Give examples)
    • When analyzing a human karyotype, scientists first look for what main features?
    • What can not be seen in a karyotype?