Understanding Disease at the Organelle Level

1) Promotes multiple areas of human development and 21st century skills, including but not limited to, the following:

Standards

NJCCCS for Science

Standard: 5.1 Science Practices: All students will understand that science is both a body of knowledge and an evidence-based, model-building enterprise that continually extends, refines, and revises knowledge. The four Science Practices strands encompass the knowledge and reasoning skills that students must acquire to be proficient in science.

Grade Level: By the end of grade 12

Strand D. Participate Productively in Science: The growth of scientific knowledge involves critique and communication, which are social practices that are governed by a core set of values and norms.

Content Statement: 1. Science involves practicing productive social interactions with peers, such as partner talk, whole-group discussions, and small-group work.
CPI: Engage in multiple forms of discussion in order to process, make sense of, and learn from others� ideas, observations, and experiences.

Standard: 5.3 Life Science: All students will understand that life science principles are powerful conceptual tools for making sense of the complexity, diversity, and interconnectedness of life on Earth. Order in natural systems arises in accordance with rules that govern the physical world, and the order of natural systems can be modeled and predicted through the use of mathematics.

Grade Level: By the end of Grade 12

Strand: A. Organization and Development: Living organisms are composed of cellular units (structures) that carry out functions required for life. Cellular units are composed of molecules, which also carry out biological functions.

Content Statement: 1. Cells are made of complex molecules that consist mostly of a few elements. Each class of molecules has its own building blocks and specific functions.
CPI: Represent and explain the relationship between the structure and function of each class of complex molecules using a variety of models.

Content Statement: 6. There is a relationship between the organization of cells into tissues and the organization of tissues into organs. The structures and functions of organs determine their relationships within body systems of an organism.
CPI: Describe how a disease is the result of a malfunctioning system, organ, and cell, and relate this to possible treatment interventions (e.g., diabetes, cystic fibrosis, lactose intolerance).

Credits

Sources:
http://abcnews.go.com/Health/breathless-bride-races-cystic-fibrosis-lung-transplant-married/story? id=15776864#.UI6khZhYXap
http://www.edhsgreensea.net/Biology/html_stuff/Cell%20Organelles.htm
http://micro.magnet.fsu.edu/cells/animalcell.html
http://www.wisc-online.com/Objects/ViewObject.aspx?ID=ap11604
http://library.thinkquest.org/12413/structures.html
http://www.oup.com/us/companion.websites/9780195305753/pdf/Organelles.pdf
http://www.mhhe.com/biosci/ap/vander/humbody/reading10.mhtml
http://www.pompe.com/en/patients/about/classifying/about-lsd.aspx
http://www.lhsc.on.ca/Patients_Families_Visitors/Genetics/Inherited_Metabolic/Mitochondria/GeneralSymptoms.htm
http://www.youtube.com/watch?v=U3F_nUR1wlA
https://sites.google.com/site/dcbiologyorganellewebquest/process
http://www.state.nj.us/education/cccs/standards/5/index.html