One of the most famous of all scientific expeditions was probably Charles Darwin's travels to the coast of South America on the HMS Beagle. There he documented various plant and animal life as well as the geology of the area. His collections and documentations of thousands of species on this five year voyage led him to his ideas of evolution and his writings On the Origin of Species and the Theory of Evolution.
Another expedition that was out of this world was that made by Neil Armstrong, Edwin (Buzz) Aldrin, and Michael Collins on their voyage to the moon on July 20, 1969. While on the moon they collected rock and soil samples and deployed a seismograph and wind particle collector. Their voyage to the moon formed the basis of our understanding of the moon today.
Other famous explorers who you may have heard of include Christopher Columbus, Ferdinand Magellan, Marco Polo, Sir Edmund Hillary, Hernan Cortes, and Lewis and Clark. To find out what they and other explorers discovered on their travels, click the link below to the ten most famous expeditions.